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ARTÍCULO ESPECIAL 375 generalizables. Concordando con esta mirada, un reciente reporte de un panel de expertos convocados por el Harvard Global Health Institute y el London School of Hygiene & Tropical Medicine identificó cuatro áreas temáticas que era necesario tener en cuenta ante futuras pandemias29. En primer término, se requiere prevenir brotes de enfermedades graves, para lo cual se necesita apoyo de la comunidad internacional para mejorar las capacidades instaladas; en segundo lugar, es necesario dar respuesta oportuna a brotes de enfermedades serias, con la participación de la Organización Mundial de la Salud; en tercer lugar, en el área de investigación, es necesario producir y compartir datos, conocimiento y tecnología, lo que requiere un trabajo multidisciplinario y normas claras para asegurar acceso a los beneficios de la investigación; y en cuarto lugar, es necesario tener un sistema global organizado para la prevención y respuesta ante estos brotes. Referencias 1. Report of an International Commission. Ebola haemorrhagic fever in Zaire, 1976. Bull World Health Organ 1978; 56 (2): 271-93. 2. WHO Fact sheet 103. 2016 January. Ebola virus disease. Disponible en http://www.who.int/mediacentre/factsheets/ fs103/en/. 3. Kanapathipillai R. Ebola virus disease-current knowledge. N Engl J Med 2014; 371 (13): e18. 4. Hawkes N. Ebola outbreak is a public health emergency of international concern. Br Med J 2014; 349: g5089. 5. Prainsack B, Buyx A. Solidarity in contemporary bioethics towards a new approach. Bioethics 2012; 26 (7): 343-50. 6. WHO Advisory Panel for Ebola Outbreak. Ethical considerations for use of unregistered interventions for Ebola viral disease. August 17, 2014. http://apps.who. int/iris/bitstream/10665/130997/1/WHO_HIS_KER_ GHE_14.1_eng.pdf?ua=1. 7. Chowell G, Nishiura H. Transmission dynamics and control of Ebola virus disease (EVD): a review. BMC Med 2014; 12 (1): 196. 8. Check Hayden E. Ebola obstructs malaria control. Nature 2014; 514 (7520): 15-6. 9. Choi JH, Croyle MA. Emerging targets and novel approaches to Ebola virus prophylaxis and treatment. Bio Drugs 2013; 27 (6): 565-83. 10. Qiu X, Wong G, Audet J, Bello A, Fernando L, Alimonti JB, et al. Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp. Nature 2014; 514 (7520): 47-53. 11. Rid A, Emanuel EJ. Ethical considerations of experimental interventions in the Ebola outbreak. Lancet 2014; 384 (9957): 1896-9. 12. Gulland A. Ebola outbreak in west Africa is officially over. BMJ 2016; 352: 243. 13. WHO. Latest Ebola outbreak over in Liberia; West Africa is at zero, but new flare-ups are likely to occur. Jan 14, 2016. http://www.who.int/mediacentre/news/ releases/2016/ebola-zero-liberia/en/. 14. Calain P, Poncin M. Reaching out to Ebola victims: Coercion, persuasion or an appeal for self sacrifice? Social Science & Medicine 2015; 147: 126-33. 15. WHO updates, October 2015. Ebola vaccines, therapies, and diagnostics. http://www.who.int/medicines/ emp_ebola_q_as/en/. 16. Heron RJL. Ebola-what have we learned from the recent outbreak? Occup Med 2016; 66: 4-7. 17. Kennedy SB, Neaton JD, Lane HC, Kieh MW, Massaquoi MB, Touchette NA, et al. Implementation of an Ebola virus disease vaccine clinical trial during the Ebola epidemic in Liberia: Design, procedures and challenges. Clin Trials 2016; 13 (1): 49-56. 18. Mendoza EJ, Qiu X, Kobinger GP. Progression of Ebola Therapeutics During the 2014-2015 Outbreak. Trends in Molecular Medicine 2016; 22 (2): 164-73. 19. Beca JP, Valdivieso F. Epidemia de Ébola: una mirada desde la infectología y de la Bioética. Boletín Complutense 2014; 11-5. 20. Gericke C. Ebola and ethics: autopsy of a failure. BMJ 2015; 350: h2105. 21. Mondragon NI, Gil de Montes L, Valencia J. Understanding an Ebola outbreak: Social representations of emerging infectious diseases. J Health Psychol 2016, Jan 7. DOI: 10.117/1359105315620294. 22. Dodd LE. Clinical trials during the Ebola crisis. Clin Trials 2016; 13 (1): 5. 23. Sands P, Mundaca-Shah C, Dzau VJ. The Neglected Dimension of Global Security-A Framework for Countering Infectious-Disease Crises. N Engl Med 2016; DOI:10.1056/NEJMsr1600236. 24. Fenet S. Towards a sustainable sharing of data & samples collected during trials effectuated in resource-limited countries. Workshop organized by the Inserm Ethical Committee, Fondation Mérieux & the Global Forum on Bioethics in Research (GFBR), 5 noviembre 2015. Disponible en http://www.fondation-merieux. org/towards-better-sharing-of-data-and-samples collected-during-trials-in-resource-limited-counÉtica y Ébola - J. P. Beca et al Rev Med Chile 2016; 144: 371-376


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