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CASOS CLÍNICOS fallecimiento1. Esta paciente en sus años finales sufrió de 2 eventos cardiovasculares, el último de los cuales originó su fallecimiento. Referencias 1. Dispenzieri A. POEMS syndrome: 2014 update on diagnosis, risk-stratification, and management. Am J Hematol 2014; 89: 214-23. 2. Chandia M, Salomone C, Bertin P, González S. Síndrome 520 de POEMS con lesión lítica aislada y hemangiomas glomeruloides. Caso clínico. Rev Med Chile 2009; 137: 680-4. 3. Viveros L, Valenzuela MA, Rojas D, Castillo J. Síndrome de POEMS. Caso clínico. Rev Med Chile 1995; 122: 546- 9. 4. Galleguillos V, Rodríguez MI, Bronfman L, Niklitscheck E, Silva M. Síndrome de POEMS: revisión a propósito de un caso. Rev Med Chile 1991; 118: 789-92. 5. Horta P, Quevedo I. Síndrome de POEMS: Caso clínico. Rev Med Chile 2004; 132: 485-8. 6. Rosser GJ, Reitböck PG, Gray MC, Warnicker P. Successful stabilization of nephropathy in a patient with POEMS (polyneuropathy, organomegaly, endocrinopathy, M-band, skin changes) syndrome on treatment with mycophenolate and steroids: a case report. J Med Case Rep 2010; 4: 63. 7. Ye W, Wang C, Cai QQ, Cai H, Duan MH, Li H, et al. Renal impairment in patients with polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy and skin changes syndrome: incidence, treatment and outcome. Nephrol Dial Transplant 2015; 0: 1-9 doi:10.1093/ndt/gfv261 8. Fakatsu A, Tamai H, Nishikawa W, Yoshida F, Takeda A, Kodera K, et al. The kidney disease of Crow-Fukase (POEMS) syndrome: a clinic-pathological study of four cases. Clin Nephrol 1991; 36: 76-82. 9. Soubrier M, Deteix P, Derray G, Dubost JJ, Sauvezie B, Chapman A, et al. Renal manifestation in POEMS syndrome. Nephrologie 1994; 15: 335-8. 10. Ji ZF, Zhang DY, Weng SQ, Shen XZ, Liu HY, Dong L. Síndrome de POEMS con afectación renal - J. Vega POEMS syndrome: a report of 14 cases and review of the literature. ISRN Gastroenterol 2012; 2012: 584287. 11. Stankowski-Drengler T, Gertz MA, Katzmann JA, Lacy MQ, Kumar S, Leung L, et al. Serum immunoglobulin free light chain measurements and heavy chain isotype usage provide insight into disease biology in patients with POEMS syndrome. Am J Hematol 2010; 85: 431-4. 12. Nakamoto Y, Imai H, Yasuda T, Wakui H, Miura AB. A spectrum of clinicopathological features of nephropathy associated with POEMS síndrome. Nephrol Dial Transplant 1999; 14: 2370-8. 13. Dispenzieri A, Kyle RA, Lacy MQ, Rajkumar SV, Therneau TM, Greipp PR, et al. POEMS syndrome: Definitions and long-term outcome. Blood 2003; 101: 2496-506. 14. Sanada S, Ookawara S, Karube H, Shindo T, Goto T, Nakamichi T, et al. Marked recovery of severe renal lesions in POEMS syndrome with high-dose melphalan therapy supported by autologous blood stem cell transplantation. Am J Kidney Dis 2006; 47: 672-9. 15. Jha PK, Vankalakunti M, Bonu R, Babu K, Ballal HS. POEMS syndrome with renal plasmacytoma and classic polyarteritis nodosa: a case report. NDT Plus 2011; 4: 406-9. 16. Machiguchi T, Yoshida H, Tamura T. Macrophage and platelet-infiltrated glomerulonephritis with interstitial angiofollicular hyperplasia in a patient with POEMS syndrome. Nephrol Dial Transplant 2001; 16: 2270-1. 17. El Karoui K, Vuiblet V, Dion D, Izzedine H, Guitard J, Frimat L, et al. Renal involvement in Castleman disease. Nephrol Dial transplant 2011; 26: 599-609. 18. Mizuiri S, Mitsuo K, Sakai K, Hayashi I, Susuki T, Nagai Y, et al. Renal involvement in POEMS syndrome. Nephron 1991; 59: 153-6. 19. Soubrier M, Sauron C, Souweine B, Larroche C, Wechsler B, Guillevin L, et al. Growth factors and proinflammatory cytokines in the renal involvement of POEMS syndrome. Am J Kidney Dis 1999; 34: 633-8. 20. Fukatsu A, Ito Y, Yuzawa Y, Yoshida F, Kato M, Miyakawa K, et al. A case of POEMS syndrome showing elevated serum interleukin 6 and abnormal expression of interleukin 6 in the kidney. Nephron 1992; 62: 47-51. Rev Med Chile 2016; 144: 516-520


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