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LABORATORIO CLÍNICO 511 The association between miRNA SNPs and HCC - W. Li et al Table 2. General characteristics of hepatocellular carcinoma patients and unaffected controls Cases (n = 498) No. (%) or mean ± SD Controls (n = 520) No. (%) or mean ± SD P value Age (years) 60.11± 11.487 54.33± 11.233 < 0.001* Gender Male 81 (16.3) 154 (29.6) < 0.001* Female 417 (83.7) 366 (70.4) Smoking status 493 Never 315 (63.9) 286 (55.0) 0.004* Ever 178 (36.1) 234 (45.0) Drinking status 490 Never 352 (70.7) 398 (76.5) 0.098 Ever 138 (27.7) 122 (23.5) HBsAg 479 Negative 83 (17.3) Positive 396 (82.7) HCV 454 Negative 17 (3.7) Positive 437 (96.3) Size of tumor foci 278 < 5 cm 117 (42.1) ≥ 5 cm 161 (57.9) Number of tumor foci 278 Single 248 (89.2) Multiple 30 (10.8) Serum levels of tumor markers ALT (U/L, in 495 subjects) 59.42±87.97 AST (U/L, in 492 subjects) 63.62±88.68 AFP (μg/L, n = 488) < 20 μg/L 182 (37.3) ≥ 20 μg/L 306 (62.7) CEA (μg/L, n = 464) 5.38 ± 31.81 CA 199 (U/ml, n = 455) 43.03 ± 76.41 HBV-DNA (n = 401) ≥ 1.000 IU/mL 170 (43.4) < 1.000 IU/mL 231 (57.6) (IU/mL, in subjects) 1588234.48 ± 4361987.758 *p value less than 0.05. Rev Med Chile 2016; 144: 508-515


Abril 2016
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